Imatinib Mesylate Cas 220127-57-1

Imatinib Mesylate Cas 220127-57-1
Safe And Effective Pharma Raw Material Imatinib Mesylate GMP Standard CAS 220127-57-1 Imatinib Mesylate Cancer Treatment Steroids Pharmaceutical High Purity Anti-cancer Imatinib Mesylate / 220127-57-1 Tyrosine-kinase Inhibitor Product Description Imatinib Introduction Imatinib, sold under the...
Product Details

Safe And Effective Pharma Raw Material Imatinib Mesylate GMP Standard CAS 220127-57-1 Imatinib Mesylate Cancer Treatment Steroids Pharmaceutical  High Purity Anti-cancer Imatinib Mesylate / 220127-57-1 Tyrosine-kinase Inhibitor

Product Description


Imatinib Introduction
 Imatinib, sold under the brand names Gleevec and Glivec, used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML). Due in large part to the development of Gleevec and related drugs having a similar mechanism of action, the five year survival rate for people with chronic myeloid leukemia nearly doubled from 31% in 1993 (before Gleevec's 2001 FDA approval) to 59% for those diagnosed between 2003 and 2009. Median survival for imatinib-treated people with gastrointestinal stromal tumors (GIST) is nearly 5 years compared to 9 to 20 months in the pre-imatinib-era.
 
 Imatinib Mesylate Basic Info.
 Other Name:Glivec;gleevec;imatinib methanesulfonate;imatinib mesilate;Imatinibmesylate;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate
 CAS:220127-57-1
 MF:C30H35N7O4S
 MW:589.71
 Assay:99%min
 Appearence:White powder
 Drug category:Anti tumor drug
 Purpose:A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).

Imatinib Mesylate Application:
 Compared to older drugs imatinib has a relatively benign side effect profile, allowing many patients to live a normal lifestyle. Imatinib is a tyrosine-kinase inhibitor. It kills cancer cells by blocking the action of

tyrosine kinases. In order to survive, cells need signaling through proteins (signal cascade) to keep them alive. Some of the proteins in this cascade use a phosphate group as an "on" switch. This phosphate group is added by a tyrosine kinase enzyme. In healthy cells, these tyrosine kinase enzymes are turned on and off as needed. In Ph-positive CML cells, one tyrosine kinase enzyme, BCR-Abl, is stuck on the "on" position, and keeps adding phosphate groups. Imatinib blocks this BCR-Abl enzyme, and stops it from adding phosphate groups. As a result, these cells stop growing, and even die by a process of cell death (apoptosis). Because the BCR-Abl tyrosine kinase enzyme exists only in cancer cells and not in healthy cells, imatinib works as a form of targeted therapy-only cancer cells are killed through the drug's action.[6] In this regard, imatinib was one of the first cancer therapies to show the potential for such targeted action, and is often cited as a paradigm for research in cancer therapeutics.

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Peptide List

Product Name

Specification

ACE 031

1 mg/vial, 10 vials/kit

Follistatin 315

1 mg/vial, 10 vials/kit

Follistatin 344

1 mg/vial, 10 vials/kit

*****************************

*****************************

MGF

2 mg/vial, 10 vials/kit

PEG - MGF

2 mg/vial, 10 vials/kit

DSIP

2 mg/vial, 10 vials/kit

TB500

2 mg/vial, 10 vials/kit

Oxytocin

2 mg/vial, 10 vials/kit

Hexarelin

2 mg/vial, 10 vials/kit

Triptorelin

2 mg/vial, 10 vials/kit

Ipamorelin

2 mg/vial, 10 vials/kit

Sermorelin

2 mg/vial, 10 vials/kit

Gonadorelin

2 mg/vial, 10 vials/kit

Tesamorelin

2 mg/vial, 10 vials/kit

BPC 157

2 mg/vial, 10 vials/kit

AOD-9604

2 mg/vial, 10 vials/kit

H 176-191

2 mg/vial, 10 vials/kit

CJC-1295

2 mg/vial, 10 vials/kit

CJC-1295 DAC

2 mg/vial, 10 vials/kit

*****************************

*****************************

GHRP-2

5 mg/vial, 10 vials/kit

GHRP-6

5 mg/vial, 10 vials/kit

Selank

5 mg/vial, 10 vials/kit

*****************************

*****************************

GHRP-2

10 mg/vial, 10 vials/kit

GHRP-6

10 mg/vial, 10 vials/kit

Epitalon

10 mg/vial, 10 vials/kit

PT-141

10 mg/vial, 10 vials/kit

Gonadorelin

10 mg/vial, 10 vials/kit

Melanotan II

10 mg/vial, 10 vials/kit


FAQ
 Order Guide
 Q1: Have your Product Quality been Approved by Third Party Lab?
 A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 Q2:How do you treat quality complaint?
 A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC ,TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 Q3: Do you Accept Sample Order?
 A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.
 Q4: Is there any discount?
 A: Yes, for larger quantity, we always support with better price.
 Q5:Do you accept VISA business credit card ?
 A:Sorry we don't accept VISA credit card,
 we'd like to accept bank transfer, Western Union or Paypal or Moneygram
 Q6:How long does it take to the goods arrived ?
 It is Depending on your location,
 For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
 For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
 Q7 Do you have any reshipment policy ?
 we have good after-sale service and re-shipment policy if the parcel lose
 Our long association with our clients has brought great benefits
 We always take the upmost care in the packaging of our products
 our clients will confirm this as even they struggle to find them without help at times.
 But in spite of our best efforts it is still possible will seize a small number of packages.
 In this circumstance we promise reship free to establish long term relationship
 Q8 :Can I get a sample?
 A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.
 
 We have formed a technology and management team that cooperate closely with some overseas Labs all speak highly of our safe shipping and goods .
please donot hesitate to contact us.


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