99% White Powder Aicar CAS: 2627-69-2 Treating Cardiovascular Diseases Lab Supply Best Quality for bodybuilding
Product Name: Aicar
Alternative Name: 5-Aminoimidazole-4-carboxamide 1-尾-D-ribofuranoside, Acadesine
Appearance: White or off-white powder
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases
AICAR is a peptide of the art name 5-aminoimidazole-4-carboxamide ribonucleotides, also known as AICA ribonucleotides, ZMP or Acadesine. It is an intermediate that produces inosine monophosphate, primarily as an AMP-activating protein kinase agonist, which means that it has the ability to promote the ability to store nutrient storage capacity.
AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain the steady state of cell energy (Hardie and Carling).
AICAR can play a role in promoting these processes because it contains the ability to penetrate heart cells and prevent the production of enzymes associated with regulation of glucose uptake and energy excretion.
Inhibition of these regulatory enzymes, the affected cells, in turn, can increase the amount of acceptable glucose and also increase their energy conversion levels. In addition, the presence of peptides has been identified to help reduce programmed cell death, and processes are also known as apoptosis
Aicar (AICA-Riboside) strongly inhibits transcription of PPARα and co-activation of PPARα. It has been shown in adipocyte studies that antagonizing lipolysis induced by isoproterenol and has been suggested for kinase cascade studies. In addition, studies have shown that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.
Studies have shown that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase) and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).
5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is a monophosphorylated derivative of AICA-riboside which can be used as an aminoimidazole carboxamide ribonucleotide invertase / inosine monophosphate cyclase hydrolase ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 kinases
Related substance (HPLC)
Total impurity ≤0.5%
100% pass 80 mesh
Loss on Drying
Total Plate Count
Yeast & Mold
SARMS powder Series:
Q1:Have your product quality been approved by Third Party Lab?
A:Yes,All products are strictly tested by our QC,confirmed by QA and approved by third party lab in China,USA,Canada,Germany,UK,Italy,France etc.So you will be assured with Good Quality if you choose us.
Q2:How do you treat quality complaint?
A:First of all,our QC department will do strict examination of our export products by HPLC,UV,GC,TLC and so on in order to reduce the quality problem to near zero.If there is a real quality problem,caused by us,we will send you free goods for replacement or refund your loss.
Q3:Do you accept sample order?
A:Yes,we accept small order from 10g,100g and 1kg for your evaluation quality of our goods.
Q4:Is there any discount?
A:Yes,for larger quantity,we always support with better price.
Q5:How long does it take to arrive?
A:It is Depending on your location,
For small order,please expect 5-7 days by DHL,UPS,TNT,FEDEX,EMS.
For mass order,please allow 5-8 days by Air,20-35 days by Sea.
Q6:Do you have any reshipment policy?
Yes we will reship for totally free if your parcles is seizd by customs unlucky,you dont need to pay any more money
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