Gamma Butyrolactone GBL-Butyrolactone for Improving Athletic

Pain Killer Powder Local Anesthetic 20-50 Mesh Benzocaine CAS 94-09-7 Description Benzocaine is used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison IVY, poison oak, poison sumac, minor cuts, or scratches. Benzocaine belongs...
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Gamma Butyrolactone GBL-Butyrolactone for Improving Athletic 
 
Product Description
Gamma-Butyrolactone (γ-butyrolactone or GBL) is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water. GBL is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug for GHB, and it is used as a recreational intoxicant with effects similar to alcohol.
GBL has been found in extracts from samples of unadulterated wines. This finding indicates that GBL is a naturally occurring component in some wines and may be present in similar products. The concentration detected was approximately 5 μg/mL and was easily observed using a simple extraction technique followed by GC/MS analysis. GBL can be found in cheese flavourings but typically results in a content of 0.0002% GBL in the final foodstuff.
GBL is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide, GBL can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.
GBL is not active in its own right; its mechanism of action stems from its identity as a prodrug of GHB. The hypnotic effect of GHB is enhanced by combination with alcohol. A 2003 rat study showed that GBL in combination with ethanol showed a potentiated hypnotic effect, as the sleep-timing measure was longer than both of the individual components combined.

 
COA


Test Items

Specification

Results

Appearance

Colorless transparent liquid

Conforms
Purity99.8%-107%99.99%
Moisture≤0.03%0.015
Density1.125-1.1.1301.127
Refractivity1.436-1.4371.4366
Diol(wt% GC)≤0.020.007
Tetrahydrofuran(wt% GC)≤0.030.02
Conclusion

Complies with Enterprise Standard


Local Anesthetic powder (Active Pharmaceutical Ingredients)

Product nameCAS No.
Benzocaine94-09-7
Benzocaine Hcl137-58-6
Lidocaine Hydrochloride73-78-9
Procaine59-46-1
Procaine hydrochloride51-05-8
Dyclonine Hydrochloride23964-57-0
Levobupivacaine Hydrochloride536-43-6
Propitocaine hydrochloride27262-48-2
Ropivacaine Mesylate 854056-07-8
Tetracaine Hydrochloride 136-47-0
Tetracaine base94-24-6
Prilocaine721-50-6
Tetracaine (dicain)94-24-6

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