It is also called acetophenetidin. Having glossy leaflets or scales-like crystals that have no odor or taste.
Melting point 134 ~ 137. Stable in air, soluble in water, slightly soluble in boiling water, slightly soluble in ether, soluble in ethanol, chloroform. It is formed through the etherification, reduction and Acetylation reaction of p-chloronitrobenzene. As chloroacetanilide antipyretic and analgesic agent. Suitable for fever, headache, neuralgia and other drugs as a compound agent.
Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin, low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic effect. Because the enzyme inhibitor makes phenacetin not to be converted into paracetamol, still showed obvious antipyretic effect, thus the antipyretic effect after the product line does not converge to paracetamol.The mild phenacetin analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.
How Phenacetin Works:
Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia.
It is metabolized in the body acetaminophen (acetaminophen).
Local Anesthetic powder (Active Pharmaceutical Ingredients)
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