Procaine HCL Cas 51-05-8

Quick detail Description Procaine HCl is a local anesthetic drug for the amino ester groups. It is mainly used to reduce the intramuscular injection of penicillin pain, and also for dental use. As the merchandise name Novocain is everywhere, in some areas procaine is generally known as...
Product Details

Quick detail

Product name

Procaine hcl

Other name

Procaine hydrochloride, aminocaine;anadolor;atoxicocaine;

CAS register number

51-05-8

EINECS

200-077-2

Molecular formula

C13H21ClN2O2

Molecular weight

272.77

Assay

98.5%

Appearance

White crystalline powder

Package

1kg/aluminium foil bag or as required

Usage

can be used as pharmaceutical material


 Description
 Procaine HCl is a local anesthetic drug for the amino ester groups. It is mainly used to reduce the intramuscular injection of penicillin pain, and also for dental use. As the merchandise name Novocain is everywhere, in some areas procaine is generally known as Novakaine. Its main role is sodium channel blockers. Because of its sympathetic, anti-inflammatory, perfusion enhancement and emotional enhancement, it is used in some countries for treatment.

Procaine hydrochloride is used to produce local or local analgesia and anesthesia by local infiltration and peripheral nerve block techniques.

The application of procaine leads to inhibition of neuronal activity. Depression causes the nervous system to become allergic, causing anxiety and vibration, resulting in mild to severe convulsions. Studies of animals have shown that the use of procaine causes an increase in dopamine and serotonin levels in the brain. Other problems may vary due to individual tolerance to procaine dose. Central nervous system excitation can cause tension and dizziness, if excessive coordination may lead to respiratory failure. Procaine may also cause myocardial weakness leading to cardiac arrest.

Procaine can also cause allergic reactions, leading to individual problems of breathing, rash and swelling. The allergic reaction to procaine is usually not against procaine itself, but its metabolite PABA. About one of about 3,000 people has an atypical form of pseudobase esterase, which does not require hydrolysis of ester anesthetics such as procaine, resulting in increased levels of narcotics in the blood and increased toxicity.

Application
 Procaine is the main ingredient of Arra Aslan (Romania) in the controversial preparation of Gerovital H3, which advocates remedial many of the effects of aging. The mainstream medical view is that these claims were carefully studied and discredited in the 1960s.

It is recommended that 1% procaine injections be used to treat extravasation complications associated with venipuncture (as well as hot flashes, ASA, steroids, antibiotics). It is also recommended to treat unintentional intra-arterial injections (10 ml 1% procaine) as it helps to relieve pain and vasospasm.
 Procaine is an occasional additive for illegal street drugs.

COA

Product name

Procaine HCl

Appearance

White crystalline powder

Assay (C13H20N2O2·HCl)

99.0% to 101.0%

99.5%

Melting point

153~158ºC

156.5~157.0ºC

Heavy metals

≤20ppm

<5ppm

Acidity

≤0.02N NaOH 0.5ml

0.3ml

Chromatographic purity

Secondary spots≤0.5%,sum≤1.0%

Conforms

Loss on drying

≤1.0%

0.06%

Residue on ignition

≤0.15%

0.03%

Bacterial endotoxins

≤0.6EU/mg

<0.6EU/mg

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