Pain killer Raw material powder Antipyretic Analgesics Pharmaceutical Raw Materials Paracetamol / Acetaminophen CAS 103-90-2
Paracetamol; 4-ACETAMIDOPHENOL; 4-ACETAMINOPHENOL;ACETAMINOPHEN
PHARMACEUTICALS; Aromatic Phenols; Intermediates&Fine Chemicals; Lipid signaling; Aromatics;inhibitor; APIs
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Antiinfectant, dispersing agent in liquid scintillation counting. Analgesic; antipyretic
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What is Paracetamol?
Paracetamol (acetaminophen) is an analgesic and feverative agent. The exact mechanism of action is unknown.
Acetaminophen for the treatment of headache, muscle soreness, arthritis, back pain, toothache, colds and fever and other situations. It relieves mild arthritis pain, but has no effect on the potential inflammation and swelling of the joint.
Paracetamol can also be used for other purposes not listed in this drug guideline.
How can I use paracetamol dosage?
Follow the instructions on the label or use the paracetamol according to the doctor's instructions.
Do not use more of this medication than recommended. Excessive paracetamol may cause serious injury. The maximum amount of adult is 1 gram (1000 mg) per dose, 4 grams per day (4000 mg). Using more paracetamol may cause harm to your liver. If you drink more than three alcoholic beverages a day, talk to your doctor before taking acetaminophen and do not use more than 2 grams (2000 milligrams) per day. If you are treating a child, please use paralyzing pain in your child's form. Carefully follow the dose instructions on the drug label. Do not give children under 2 years of age without a doctor's advice.
Use a special dose to measure the spoon or cup to measure the liquid form of acetaminophen, rather than the ordinary spoon. If you do not have a dosimeter, ask your pharmacist. Before each use, you may need to shake the liquid. Follow the instructions on the drug label.
Before you swallow, you must thoroughly chew the paracetamus chewable tablets.
When handling acetaminophen disintegration tablets, make sure to dry. Put the tablet on your tongue and it will begin to dissipate immediately. Do not swallow your tablet. Let it dissolve in the mouth, do not chew.
To use acetaminophen effervescent particles, dissolve a pack of particles in at least 4 ounces of water. Stir the mixture and drink immediately. To ensure that you are able to get the entire dose, add a little water to the same glass and gently rotate and drink immediately.
Do not treat paracetamol rectal suppositories. It is only for your rectum. Wash hands before and after suppository.
Try to empty your intestines and bladder before using acetaminophen suppositories. Remove the outer packagings from the suppositories prior to insertion. Avoid the treatment of suppositories for too long, otherwise it will dissolve in the hands.
In order to obtain the best results from the suppository, lie down and insert the suppository tip into the rectum first. Hold the emboli for a few minutes. After the insertion will quickly melt, and hold it feel little or no discomfort. Avoid using the bathroom immediately after inserting the emboli.
White or almost white ,crystalline powder.
Not more than0.5%
Impurity(chloroacetanilide)not more than 10 ppm
any other impurity not more than 0.05%
Total of other impurities not more than 0.1%
Residue on ignition
Not more than 0.1%
Not more than 0.014%
Less than 0.014%
Not more than 0.02%
Less than 0.02%
Not more than 0.001%
Less than 0.001%
Not more than 0.005%
Less than 0.005%
Limit of Pchloroa
Not more than 0.001%
Less than 0.001%
Readily carbonizable substances
Residual content of acetic acid is limited by the test of loss on dryingnot more than0.5%
Conclusion: Complies with USP34 / BP2011
1. Medical uses:
Paracetamol is used for reducing fever in people of all ages. The World Health Organization (WHO) recommends that paracetamol be used to treat fever in children only if their temperature is greater than 38.5 掳C (101.3 掳F). The efficacy of paracetamol by itself in children with fevers has been questioned and a meta-analysis showed that it is less effective than ibuprofen.
Paracetamol is used for the relief of mild to moderate pain. The use of the intravenous form for pain of sudden onset in people in the emergency department is supported by limited evidence.
The American College of Rheumatology recommends paracetamol as one of several treatment options for people with arthritis pain of the hip, hand, or knee that does not improve with exercise and weight loss.A 2015 review, however, found it provided only a small benefit in osteoarthritis.
Paracetamol has relatively little anti-inflammatory activity, unlike other common analgesics such as the NSAIDs aspirin and ibuprofen, but ibuprofen and paracetamol have similar effects in the treatment of headache. Paracetamol can relieve pain in mild arthritis, but has no effect on the underlying inflammation, redness, and swelling of the joint.It has analgesic properties comparable to those of aspirin, while its anti-inflammatory effects are weaker. It is better tolerated than aspirin due to concerns about bleeding with aspirin.
Low back pain
Based on a systematic review, paracetamol is recommended by the American College of Physicians and the American Pain Society as a first-line treatment for low back pain.However, other systematic reviews concluded that evidence for its efficacy is lacking.
Paracetamol combined with NSAIDs may be more effective for treating postoperative pain than either paracetamol alone or NSAIDs alone.
2. Veterinary use:
Paracetamol has also been widely used in the veterinary area, the effect has been proved by the treatment of cats, dogs, snakes, and other animals without or with rare side effects.
How to Take Paracetamol?
How much you can take depends on your age, your weight, the type of paracetamol you're taking and how strong it is. For example:
Adults can usually take one or two 500mg tablets every 4-6 hours, but shouldn't take more than 4g (eight 500mg tablets) in the space of 24 hours.
Children under 16 need to take a lower dose, depending on their age or weight - check the packet or leaflet, or ask a pharmacist or doctor for advice. For very young children, paracetamol liquid is given using a measuring spoon or an oral syringe.
Paracetamol should start to work within an hour and the effect usually lasts several hours. Don't take more than the recommended dose if it isn't relieving your symptoms.
Adults can take ibuprofen at the same time if necessary, but this isn't usually recommended for children.
A: Keep out of the reach and sight of children.
B: Store below 25 C in a dry place, protected from light.
C: Do not use Paracetamol tablets after the expiry date stated on the label/carton/bottle. The expiry date refers to the last day of that month.
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