Anti Estrogens Steroid Powder Tamoxifen Citrate for Female

Anti Estrogens Steroid Powder Tamoxifen Citrate for Female
Anti Estrogens Steroid Powder Tamoxifen Citrate/Nolvadex for Female Product details Description : Tamoxifen citrate is a non-steroidal agent that demonstrates potent antiestrogenic properties. The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors...
Product Details

Anti Estrogens Steroid Powder Tamoxifen Citrate for Female


Product details

Product Name

Nolvadex

Chemical Name

Tamoxifen Citrate,Tamoxifene

CAS Number

10540-29-1

EINECS Number

259-415-2

Molecular Formula

C32H37NO8

Molecular Weight

563.64

Molecular Structure

图片11.jpg

Melting Point

140-144 °C

Assay

99.5%

Appearance

White powder

 

Description:

Tamoxifen citrate is a non-steroidal agent that demonstrates potent antiestrogenic properties. The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. With the tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an antiestrogenic effect is achieved. Since many forms of breast cancer are responsive to estrogen, the ability of tamoxifen citrate to block its action in such cells has proven to be a very effective treatment. It is also utilized successfully as a preventative measure, taken by people with an extremely high familial tendency for breast cancer. While Nolvadex is effective against estrogen, it is not our strongest available remedy. We now have the drug Arimidex (see: Arimidex) available to us, which notably prevents estrogen from being manufactured in the first place. Altering the effect of estrogen in the female body can cause a level of discomfort, so antiestrogens are most bearable when used after the point of menopause. Since Nolvadex is milder in comparison, it is more widely applicable and usually the first treatment option.

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Specification

Test Items

Specification

Test Results

Description

White crystalline powder

White crystalline powder

Identification

IR , UV conform

Conform

Loss on drying

≤0.5ml

0.21ml

Residue on ignition

Not more than 0.2%

0.06ml

Iron

Not more than 0.005%

0.0018%

Heavy metals

Not more than 0.001%

0.0006%

Related substances

Total: Not more than 1.0%
Individual: Not more than 0.5%

0.32%
0.14%

E-isomer

Not more than 0.3%

0.19%

Organic volatile impurities

Conforms

Conforms

Assay

99.0~101.0%

99.51%

Conclusion

Conform with USP30


Usage of Tamoxifen

The goods to anti-estrogen fertility inducer, the objects in dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases; It is used as a first line defense against breast cancer. Nolvadex or Tamoxifen citrate, a non-steroidal antiestrogen for oral administration, is commonly by athletes as a post cycle therapy drug to reduce or prevent the formation of excess estrogens that can lead to oily skin, acne, fluid retention, and gynecomastia.


Applications:

For the treatment of advanced, recurrent breast cancer and ovarian cancer and other illnesses. Used as an antineoplastic raw materials.

Biological Activity: Estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo . Also high affinity agonist at the membrane estrogen receptor GPR30.


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