Fasoracetam is a research chemical of the racetam family.It is a nootropic, and has been in clinical trials for vascular dementia and attention deficit hyperactivity disorder.
Fasoracetam appears to agonize all three metabotropic glutamate receptors and has improved cognitive function in rodent studies.It is orally available and is excreted mostly unchanged via the urine.
Fasoracetam was discovered by scientists at the Japanese pharmaceutical company Nippon Shinyaku, which brought it through Phase 3 clinical trials for vascular dementia, and abandoned it due to lack of efficacy.
Scientists at Children's Hospital of Philadelphia led by Hakon Hakonarson identified fasoracetam's potential use in attention deficit hyperactivity disorder.Hakonarson started a company called neuroFix Therapeutics, LLC to try to bring the drug to market for this use; neuroFix acquired Nippon Shinyaku's clinical data as part of its efforts.neuroFix was acquired by Medgenics in 2015.Medgenics changed its name to Aevi Genomic Medicine in 2016.Clinical trials in adolescents with ADHD who also have mGluR mutations started in 2016.
Benefits of Fasoracetam:
The benefits of fasoracetam are mostly in anecdote, but there are some studies to suggest a correlation. Given that there are millions of children and adolescents using amphetamine-based ADHD medication, studies testing fasoracetam effects is a good sign. Even better, fasoracetam has made it to phase II and III of clinical trials, which could suggest a high effectiveness for this purpose. As of June 2016, the drug was still in these trials.
According to anecdotal evidence on fasoracetam benefits, the concentration and stimulation benefits are moderate. One person likened the stimulation effects to noopept and another said it was more of an energy boost than stimulation.
Aside from these focus and concentration related benefits, there is evidence for neuroprotective effects as well. One rat study showed that fasoracetam could prevent memory disruptions. This is common amongst the racetam line of drugs and makes sense that fasoracetam would display many of these same properties.
What is noopept?
Noopept, a strong cognitive enhancer, was developed in Russia in the early 2000s for the treatment of alcohol induced brain damage.
A mind-turning supplement, Noopept is a powerful substance which is able to cross the blood brain barrier. It works primarily by binding to glutamate receptors and exerting strong neuroprotective effects on the brain.Its highbio-availability also means it is fast acting and may have a cumulative effect.
While it is most well known as a brain supplement, Noopept also increases coordination and improves mood. It is able to help fight fatigue and avoid caffeine withdrawals with no noticeable side effects. It makes a great study aid, since it will not cause insomnia.
Some research also indicates that this supplement may help to prevent oxidization damage to the brain. It also works to treat alcohol related brain damage (this was actually the original purpose for its development).
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