Injectable Steroids Hormone Tibolone Livial Powder for Anti Aging

Injectable Steroids Hormone Tibolone Livial Powder for Anti Aging
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Product Details

Injectable Steroids Hormone Tibolone Livial Powder for Anti Aging


Quick details 

CAS

5630-53-5

Synonyms

LIVIELLA;LIVIAL

EINECS

227-069-1

Molecular Formula

C21H28O2

EINECS:

245-669-1

Molecular weight

312.45

chatacter

White powder.

Structure

图片13.jpg

Product Description:

Tibolone (Livial/Liviella) is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.

Tibolone (INN, USAN, BAN) (brand name Livial, Tibofem), also known as 7-methylnoretynodrel, is a synthetic steroid drug with estrogenic, progestogenic, and weak androgenic actions which was introduced in 1988 and is used widely in Europe, Asia, Australasia, and, with the exception of the United States (where it is not available), the rest of the world. It is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.

Tibolone is a 19-nortestosterone derivative and is related structurally to other 19-nortestosterone progestins. It is the 7-methyl derivative of noretynodrel.


Application


Tibolone is used to mimic the activity of natural estrogenic estrogen and progesterone in vivo.It helps to restore the natural balance of these hormones.

Tibolone is a female sex hormone,sometimes called hormone replacement therapy(HRT).Tibolone is decomposed into hormones in vivo and then has a similar effect to HRT,a HRT containing estrogen and progesterone.


Irinotrexil can be used to alleviate symptoms that occur when a female body no longer produces certain hormones(such as estrogen).This may occur after a postmenopausal,also known as a change of life,or removal of the ovaries after surgery.

Tibolone can also be used to prevent your bones from becoming brittle.In general,this drug is used to treat women who have experienced more than one year of menopause(life change)lacking estrogen-related symptoms.

Tibolone can include the replacement of lost hormones,leading to improved symptoms,including hot flushing,night sweats,dry or vaginal irritation,and loss of libido.Tibolone can also reduce the possibility of bone brittleness and rupture by preventing osteoporosis.


COA


TEST ITEMS

SPECIFICATION

RESULTS

Description

Light yellow or almost white crystalline powder

Light Yellow powder

Identification

IR

Positive

Assay

97.0~103.0%

99.37%

Melting Point

70~80°C

70.5~76.5°C

Specific Rotation

+22~+26°

+23.09°

Loss On Drying

0.5%max

0.25%

Residue On Ignition

0.1%max

0.05%

Heavy Metals

20PPm max

<20PPm

Organic Volatile Impurities

Meets the requirement.

Conforms

Related Substances

Single Impurity:1.0%max

<1.0%

Total Impurities:2.0%max

<2.0%

Conclusion

The specification conforms to enterprise standard.


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