Basic Overview :
White Crystalline Powder
Benzyl alcohol is an aromatic alcohol with the formula C7H8O . The benzyl group is often abbreviated "Bn" (not to be confused with "Bz" which is used for benzoyl), thus benzyl alcohol is denoted as BnOH. Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor. It is a useful solvent due to its polarity, low toxicity, and low vapor pressure. Benzyl alcohol is partially soluble in water (4 g/100 mL) and completely miscible in alcohols
Benzyl alcohol is produced naturally by many plants and is commonly found in fruits and teas. It is also found in a variety of essential oils including jasmine, hyacinth, and ylang-ylang.It is also one of the chemical compounds found in castoreum. This compound is gathered from the beaver plant food.
Benzyl alcohol has nearly the same refraction index of quartz and wool fibre. If a clear quartz object is immersed in benzyl alcohol, it becomes almost invisible. This has been used as a method to non-destructively recognize if an object is made of true quartz or not (see crystal skull). Similarly, white wool immersed in benzyl alcohol also becomes almost invisible clearly revealing contaminants such as dark and medullated fibres and vegetable matter.
Application of Dexamethaslo:
Benzyl alcohol used as ointment's preservatives, fiber, nylon and plastic film's desiccant, PVC stabilizers, photographic developer, solvent of acetate fiber, ink, paint, paint, epoxy resin coating, dye, such as gelatin, casein, shellac , intermediate for preparing benzyl ester or ether. Also used for preparing spices and flavoring agent ,additives to soap, perfume, cosmetics and other products. Because of index and quartz and wool fiber having nearly the same refractive , so as to identify agents of quartz and wool fiber. In perfumery industry used as a fixative and diluent
Benzyl alcohol hydroxyl is very lively, it can react with benzene to generate two phenyl methane, and acrylonitrile reaction of N- benzyl acrylamide (Ritter reaction), can also reaction with halogenated phosphorus and halogen acid to benzyl halide. Halogenated benzyl and phenyl methanol are benzyl 's(Ben Jiaji) chemical reagent, used to carboxylic acid and alcohol hydroxyl benzyl protecting group. Benzyl protecting group very easily take off by hydrogenation. In addition, benzyl alcohol are also likely to be more oxidants oxidized to benzoic acid, if oxidized with nitric acid, with the different concentration and temperature , can generate aldehydes or acids.
When the injection of penicillin, in order to prevent the patient from strong pain , often use benzyl alcohol for anesthesia, this pain will not be too strong, so the benzene methanol is also known as "painless water". However, a common side effects soon found on clinically: gluteal muscle contracture. This is because the benzyl alcohol is not easy to be absorbed by human body, long-term accumulation on the injection site, will cause the surrounding muscle necrosis, serious, and even affect the development of bone.
Benzyl alcohol has low acute toxicity with an LD50 of 1.2 g/kg in rats. It oxidizes rapidly in healthy individuals to benzoic acid, conjugated with glycine in the liver, and excreted as hippuric acid. Very high concentrations can result in toxic effects including respiratory failure, vasodilation, hypotension, convulsions, and paralysis.
Benzyl alcohol is toxic to neonates, it is associated with the gasping syndrome. Benzyl alcohol has been reported to cause skin allergy.
Benzyl alcohol is severely toxic and highly irritating to the eye. Pure benzyl alcohol produces corneal necrosis. Benzyl alcohol is not considered to be a carcinogen and no data are available regarding teratogenic or reproductive effects.
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