Pharmaceutical Local Anesthetic Powder Lidocaine Hydrochloride

Pharmaceutical Local Anesthetic Powder Lidocaine Hydrochloride
USP High Purity Lidocaine Hydrochloride Lidocaine HCL Lidocaine HCI CAS 73-78-9 Local Anesthetic Pain Relief
Product Details

Quick Detail:


Product NameLidocaine Hydrochloride
SynonymsLidocaine HCL; Lidocaine HCI; 2-DIETHYLAMINO-N-(2'6'-DIMETHYLPHENYL)ACETAMIDE HCL;2-DIETHYLAMINO-N-[2,6-DIMETHYLPHENYL]ACETAMIDE HCL;ALPHA-(DIETHYLAMINO)-2',6'-ACETOXYLIDIDE HYDROCHLORIDE;A-(DIETHYLAMINO)-2 6-DIMETHYLACETANILIDE HYDROCHLORIDE;LIGNOCAINE HYDROCHLORIDE;LIDOCAINE HYDROCHLORIDE;LIDOCAINE HCL;2-(diethylamino)-n-(2,6-dimethylphenyl)-acetamidmonohydrochloride
CAS73-78-9
MFC14H23ClN2O
MW270.8
EINECS200-803-8
Product CategoriesAPI;Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Research Chemical;Pharma materials
AppearanceWhite crystalline powder
Assay99.52%
StandardUSP
Mini Order100g
Usage

Local anesthesic;Na+ channel blockerAnesthetic (local); antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic.

Description and Application:


Lidocaine hydrochloride is a white powder without smell and with a bitter taste that is used both in

human and veterinary medicine. The drug is also known as lignocaine hydrochloride, and is used as

a local anesthetic and to regulate certain medical problems related to heart rhythm. Injections of it are used to provide local anesthesia during various minor surgical procedures. It is also available in

various topical preparations, such as gels, sprays, creams, and ointments that are usually applied to

the skin or the mucous membranes. This drug was first manufactured in Sweden in 1943 and was then named xylocaine.


The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and

intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface

anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for

subdural and epidural anesthesias; lidocaine, on the other hand, has the advantage of a rapid onset

of action. Epinephrine (aka adrenaline) vasoconstricts arteries reducing bleeding and also delays

the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia

several formulations are available that can be used e.g. for endoscopies, before intubations etc.

Buffering the pH of lidocaine makes local freezing less painful. Lidocaine drops can be used on the

eyes for short ophthalmic procedures.

Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia (a

complication of shingles), though there is not enough study evidence to recommend it as a

first-line treatment. IV lidocaine also has uses as a temporary fix for tinnitus. Although not

completely curing the disorder, it has been shown to reduce the effects by around two thirds.
Lidocaine hydrochloride injection administered intravenously or intramuscularly, is specifically

indicated in the acute management of ventricular arrhythmias such as those occurring in relation

to acute myocardial infarction, or during cardiac manipulation, such as cardiac surgery.

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