MK-677 / Ibutamoren
Ibutamoren Mesylate / MK-0677 / Crescendo / IBUTAMORIN
MK-677;2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate;(R)-1'-(2-Methylalanyl-O-benzyl-D-seryl)-1-(Methylsulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidine] Mesylate;Crescendo;IbutaMoren Mesylate(MK-677);MK-667;N-[1(R)-1,2-Dihydro-1-methanesulfonylspiro-3H-indole-3,4′-piperidin)-1′-yl]carbonyl-2-(phenylmethoxy)-ethyl-2-amino-2-methylpropanamide methanesulfonate;IBUTAMORIN
SARMs(Selective androgen receptor modulator)
White to yellowish-white crystalline powder
Super discreet Disguised
SARM / Effective treatment of muscle wasting, obesity and osteoporosis / Bodybuilding
Introduction of MK-677:
Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191) is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity.
MK-677 is an orally administered growth / hormone secretagogue originally developed by Reverse Pharmacology. A secretagogue is the term for a substance that chemically signals for the pituitary gland to secrete . In other words, MK-677 could be compared to peptides like GHRP-6 or Ipamorelin, only it doesn't require any injections nor does it have any side effects like GHRP-6. This GHS (Growth / Hormone Secretagogue) was developed in an aim to combat such conditions as muscle wasting, obesity and osteoporosis. It was also targeted towards treatment of elderly hip fracture patients, so there are a myriad of studies done on safety.
Our Most Popular SARMs and Short Introduction:
Enobosarm (Ostarine, MK-2866, GTx-024) - affects both muscle and bone, intended mainly for osteoporosis but also general treatment for andropause and reversing muscle sarcopenia in the elderly and for cachexia in cancer patients.
Pharmacological profile similar to that of enobosarm, Ostarine,MK-2866.
A growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly.
Partial agonist, intended mainly for treatment of benign prostatic hypertrophy.
It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease.
AICAR acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown.
Related Sarm Powder
Ostarine; MK-2866; Enobosarm
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